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recombinant human light tnfsf14 protein  (R&D Systems)


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    R&D Systems recombinant human light tnfsf14 protein
    Recombinant Human Light Tnfsf14 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant human light tnfsf14 protein/product/R&D Systems
    Average 94 stars, based on 22 article reviews
    recombinant human light tnfsf14 protein - by Bioz Stars, 2026-05
    94/100 stars

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    Image Search Results


    A. The abundance of total IHL isolated from WT and Il-17a -/- mice is quantified (N = 4-6 per group). B. Total number of IHL isolated from WT and Il-17a -/- mice reared on control or DDC diet is normalized to liver weight (N = 4-6 per group). C. The proportion of CD45 + cells in the IHL as determined by flow cytometry (N = 4-6 per group). D. (Left panel) CD4 + T cells abundance in gated CD45 + immune cells, and (Right panel ) the proportion of LIGHT + cells in the CD4 + T cell fraction (N = 3 per group). E. (Left panel) NK T cell abundance in gated CD45 + immune cells, and (Right panel ) proportion of LIGHT + cells in the NK T cell fraction (N = 4-6 per group). F. LIGHT positivity in CD4 + T cell subsets, Th1, Th2, Th17, and T-reg, was determined by flow cytometry (N = 3 per group). G. WT primary mouse splenocytes when stimulated with PMA/ionomycin or vehicle display (left panel) a similar proportion of CD3 + CD4 + T cells, (middle panel) an increased abundance of IFNγ + CD 4 + T cells and (right panel) an increased proportion of LIGHT + CD4 + T cells (N = 3 per group). H. The expression of pro-fibrogenic genes ACTA2, COL1A1, PDGFRA and CTGF is elevated in primary human hepatic stellate cells when stimulated with recombinant LIGHT (N = 3 per group). * - p < 0.05, ** - p < 0.01, *** - p < 0.005, **** - p < 0.001.

    Journal: PLOS One

    Article Title: Genetic ablation of interleukin-17A augments fibrosis in a mouse model of cholestatic liver injury

    doi: 10.1371/journal.pone.0342251

    Figure Lengend Snippet: A. The abundance of total IHL isolated from WT and Il-17a -/- mice is quantified (N = 4-6 per group). B. Total number of IHL isolated from WT and Il-17a -/- mice reared on control or DDC diet is normalized to liver weight (N = 4-6 per group). C. The proportion of CD45 + cells in the IHL as determined by flow cytometry (N = 4-6 per group). D. (Left panel) CD4 + T cells abundance in gated CD45 + immune cells, and (Right panel ) the proportion of LIGHT + cells in the CD4 + T cell fraction (N = 3 per group). E. (Left panel) NK T cell abundance in gated CD45 + immune cells, and (Right panel ) proportion of LIGHT + cells in the NK T cell fraction (N = 4-6 per group). F. LIGHT positivity in CD4 + T cell subsets, Th1, Th2, Th17, and T-reg, was determined by flow cytometry (N = 3 per group). G. WT primary mouse splenocytes when stimulated with PMA/ionomycin or vehicle display (left panel) a similar proportion of CD3 + CD4 + T cells, (middle panel) an increased abundance of IFNγ + CD 4 + T cells and (right panel) an increased proportion of LIGHT + CD4 + T cells (N = 3 per group). H. The expression of pro-fibrogenic genes ACTA2, COL1A1, PDGFRA and CTGF is elevated in primary human hepatic stellate cells when stimulated with recombinant LIGHT (N = 3 per group). * - p < 0.05, ** - p < 0.01, *** - p < 0.005, **** - p < 0.001.

    Article Snippet: Cells were rested for 4 hours and stimulated with medium containing vehicle or recombinant human LIGHT (664-LI, R&D systems, Minneapolis, MN) for 72 hours refreshing the medium at 48 hours.

    Techniques: Isolation, Control, Flow Cytometry, Expressing, Recombinant